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Is it customary to get a biopsy to rule out cancer?

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  • Is it customary to get a biopsy to rule out cancer?

    I've had 3 negative urine cytologies. A CT scan (IVP) showed no abnormalities. The gyn who did my cysto and hydro promised me he was doing a biopsy as well but he didn't. I'm not feeling like I need one but I'm wondering if everyone else is having them done?

  • #2
    I had my uro do my hydro/cysto and yes he did do a biopsy as well. For me I'm really happy he did it of course to rule out cancer (I used to be a smoker and smoking is the #1 cause of bladder cancer so I was happy to rule that out) but also because when he looked at my bladder during my hydro it LOOKED normal he said, which I freaked out and started crying because how could I have all these problems and still have a NORMAL looking bladder. When the biopsy results came back it showed a ton of mast cells which is what my uro finally used to determine that yes in fact I do def have IC. I ask your dr about it but if they said that they are sure you have IC after looking at the hydro then he was probably confident that you didn't have cancer?

    I have been diagnoised for 6 1/2 years now. I have taken a long break from the ICN but really miss helping out my fellow IC patients and want to get back into posting.
    1st hydro 4/07 showed no visible signs of IC but tons of mast cells in all my biopsy samples which did prove IC.
    2nd hydro 4/13/09 showed dark purple glomerulations and I had a capacity of 450 cc's. This hydro proved that my IC had progressed.
    I have tried every oral medication as well as rescue instills and DMSO.

    I have been lucky enough to see Dr Hanno, the top IC specialist in PA who has told me due to the fact that I have not responded to any "standard" treatments that I have a severe, end stage case of IC with a horrible quality of life (didn't have to tell me that last part!)

    Proud wifey of Shane, mommy to Griffin, and step-mom to Logan and Gage
    Also proud mom to the best Bullmastiff on earth, Claus


    • #3
      I had biopsies done, but my father had bladder cancer so it was a huge fear for me --- I mentioned it to my uro and he said they would do the biopsies to be certain. That was 32 years ago and I believe there are other ways to rule out bladder cancer now.

      Stay safe

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      • #4
        WHen I had my regular cystoscopy that Dx my IC, the urogyne did not take any biopsies either. He said that biopsies should only be done if there is anything suspicious looking. So I am guessing they know what to look for, or should I say hoping they know what to look for.


        • #5
          Biopsies were taken during my hydro.


          • #6
            thanks everyone.

            Is a biopsy the only way to see mast cells?

            Is the treatment different if you have mast cells but no glomerulations? I'm still of the opinion that despite whether they find mast cells or glomerulations they still don't have a definitive treatment and you're still just guessing at what might work and trial and error.

            I just saw the new uro and she was happy w/ the hydro the gyn saw and didn't see the need to do another and frankly, while I don't put much faith in that gyn, I'm not thinking treatment decisions would be much different if gloms. were seen. I also don't want to go through another hydro, some part of that procedure and /or the D & C made me much worse.

            She did a pelvic exam, should have said no, it didn't hurt at the time but it does now! Started soon as I left the building. She wants to do full urodynamics and I'm thinking this body doesn't want to be messed w/ anymore. I don't think what it will yield will be worth how much worse I might get.

            I'm gonna call the physiotherapist.

            Any thoughts? Thanks for your help:-)


            • #7
              Hi Holly...I got worse too after my cysto/hydro/biopsy, and that was now 4 months ago...I am hoping I will get better soon...