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Fascinating Study On Diverticulosis!

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  • Fascinating Study On Diverticulosis!

    Okay this study caught my eye for two reasons. IC patients often struggle with a host of bowel issues but, even more importantly, this research demonstrates that they might have been wrong about why pouches develop in the bladder wall. The previous rationale was that diverticulosis occurred due to increased pressure in the colon, perhaps relating to constipation. Thus, for decades, doctors advised patients to eat more fiber, etc. etc. This study shows that eating more fiber not only didn't help but appeared to create more risk? I know.. it's confusing right?

    While the researchers admit that noone really knows why diverticulosis occurs, they now suspect that gut flora might be part of the problem. Fascinating. Does it mean reducing fiber? I don't read it that way. As an IC patient, being constipated almost always makes the bladder more comfortable. I think eating enough fiber so that you are regular is the ideal goal. For me, that's Ezekiel cereal in the morning, one apple a day and a few good servings of veggies and/or other high fiber foods. - Jill

    Diets High in Fiber Won't Protect Against Diverticulosis
    Released: 1/23/2012 2:00 PM EST

    Source: University of North Carolina at Chapel Hill School of Medicine

    Newswise — CHAPEL HILL, N.C. – For more than 40 years, scientists and physicians have thought eating a high-fiber diet lowered a person’s risk of diverticulosis, a disease of the large intestine in which pouches develop in the colon wall. A new study of more than 2,000 people reveals the opposite may be true.
    The study, conducted by researchers at the University of North Carolina at Chapel Hill School of Medicine , found that consuming a diet high in fiber raised, rather than lowered, the risk of developing diverticulosis. The findings also counter the commonly-held belief that constipation increases a person’s risk of the disease.
    “Despite the significant morbidity and mortality of symptomatic diverticulosis, it looks like we may have been wrong, for decades, about why diverticula actually form,” said Anne Peery, MD, a fellow in the gastroenterology and hepatology division at UNC and the study’s lead researcher. The study appears in the February 2012 issue of the journal Gastroenterology.

    “While it is too early to tell patients what to do differently, these results are exciting for researchers,” said Peery. “Figuring out that we don’t know something gives us the opportunity to look at disease processes in new ways.” Diverticulosis affects about one-third of adults over age 60 in the United States. Although most cases are asymptomatic, when complications develop they can be severe, resulting in infections, bleeding, intestinal perforations and even death. Health care associated with such complications costs an estimated $2.5 billion per year.

    Since the late 1960s, doctors have recommended a high-fiber diet to regulate bowel movements and reduce the risk of diverticulosis. This recommendation is based on the idea that a low fiber diet will cause constipation and in turn generate diverticula as a result of increased pressure in the colon. However, few studies have been conducted to back up that assumption. “Our findings dispute commonly-held beliefs because asymptomatic diverticulosis has never been rigorously studied,” said Peery.

    The UNC study is based on data from 2,104 patients aged 30-80 years who underwent outpatient colonoscopy at UNC Hospitals from 1998-2010. Participants were interviewed about their diet, bowel movements and level of physical activity. “We were surprised to find that a low-fiber diet was not associated with a higher prevalence of asymptomatic diverticulosis,” said Peery. In fact, the study found those with the lowest fiber intake were 30 percent less likely to develop diverticula than those with the highest fiber intake. The study also found constipation was not a risk factor and that having more frequent bowel movements actually increased a person’s risk. Compared to those with fewer than seven bowel movements per week, individuals with more than 15 bowel movements per week were 70 percent more likely to develop diverticulosis.

    The study found no association between diverticulosis and physical inactivity, intake of fat, or intake of red meat. The disease’s causes remain unknown, but the researchers believe gut flora may play a role.

    Peery said more research is needed before doctors change dietary recommendations, but the study offers valuable insights on diverticulosis risk factors. “At this time, we cannot predict who will develop a complication, but if we can better understand why asymptomatic diverticula form we can potentially reduce the population at risk for symptomatic disease,” said Peery.

    UNC co-authors include Patrick Barrett, Doyun Park (currently at Albert Einstein College of Medicine), Albert Rogers, Joseph Galanko, Christopher Martin and Robert Sandler, gastroenterology & hepatology division chair. The research was supported by grants from the National Institutes of Health.
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  • #2
    I have felt that my colon has a lot to do with my symptoms.
    The first colonoscopy I ever had took away all my bladder symptoms
    for 2 weeks. I thought I was cured! (this was before my diagnosis of IC)
    I have 4 to 7 bowel movements a day that are not diarreah.My GI Dr.
    says I need more fiber.What? the discomfort from all of this puts a lot of pressure on my Urethra and vagina.there is a connection,I just don't know what it is.


    • #3
      For some reason constipation also makes me feel like Im retaining urine. Thus inducing a flare
      Diagnosed with IC October 2009- through bladder biopsy (no glomerations or hunners ulcers found, just irritation)

      I have moderate-severe IC

      Currently stopped taking all medications due to pregnancy