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Medications that worsen IC

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  • Medications that worsen IC


    I have not posted here in a long time, so in a way I am a newbie. I have a question about medications that cause IC flare ups. Years ago I was diagnosed with depression, and knew nothing about IC. I just knew my bladder would hurt like crazy sometimes. I tried one medicine after another and they all seemed to cause me to have bladder/pelvic pain. When I would stop the medication, it would get better. Then we would try something else, and it would come back. I tried about 5 different meds. My doctor didn't say it, but I could tell she thought it was all in my head. I got tired of the pain, and decided to just stop trying to find something for my depression.

    It was a relief to find out that this awful pain was real and that others suffer from it and it has it name!! Now I am trying again to do something about my depression. The doctor put me on Lexapro. My IC has been pretty much under control for about a month. I started the medicine on Tuesday of this week. My IC started acting up Tuesday of this week. Coincidene? I don't know.

    Has anyone else foundt that certain medicines cause IC flares? I know ibuprofen and epinephrine can cause problems, but anyone have trouble with depression/anxiety meds? Thanks!

  • #2
    Lexapro has helped my IC, but I know others here have said it flared them so it's certainly possible. It could also be that as your body adjusts to this new med it will throw your bladder for a few days.

    Seems like some antidepressants work well for some folks in terms of not flaring their IC and the same med can wreak havoc on another person's bladder. It's so individual.

    Diagnosed August 2001

    Current IC meds: Elmiron (since 2001), Levaquin (one pill after intercourse to prevent UTIs), Effexor (for depression & anxiety)

    Past IC meds: Amitriptyline (Elavil), Hydroxyzine (Vistaril), Detrol LA, Lexapro (for depression & anxiety, but also helped my IC) (They all helped, but I was able to discontinue them.)

    I've been virtually symptom free and able to eat & drink whatever I'd like for about 8 years now.


    “We who lived in concentration camps can remember the men who walked through the huts comforting others, giving away their last piece of bread. They may have been few in number, but they offer sufficient proof that everything can be taken from a man but one thing: the last of the human freedoms -- to choose one's attitude in any given set of circumstances, to choose one's own way.” ~ Viktor Frankl

    “You cannot control what happens to you, but you can control your attitude toward what happens to you, and in that, you will be mastering change rather than allowing it to master you.” ~ Brian Tracy