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  • #1

    DMSO...anyone very knowledgeable?

    I havent posted in a while because Ive been very ill, but I still manage to find time to poke around the net researching and whatnot.. Anyway, I was curious as to what DMSO actually is, so I looked it up and While reading an article on wikipedia, I found out that it is a preservative and is used to preserve organs and stuff. I kinda have to wonder why they are trying to treat IC with a preservative, when that is one of the triggers for most people. I'm no scientist, but I'm kinda thinking that maybe this doesn't make too much sense.

    Does anyone know a bit more about this.. or just DMSO really.

    -Anne Katherine

    Diagnosed: IC-2004' Endometriosis- 2000,TMJ - 2004, Osteoporosis-2005, IBS - 2005
    Peptic Ulcer-2005, PFD-2005, CFS - 2006, ADD - 1996 Bipolar disorder -2007. Other shinanigans: pelvic adhesions, Migraines, Cluster Headaches, fatigue, stomach ulcers, ovarian cysts, allergies, severe PMS.[/COLOR]
    Since February, I have had MRSA 7 times, was hospitalized for IV a/bs, and will be taking Tetracycline for the next 6 months. In April, my gyno found that not only did I also have a currently active infection of Epstein Barr Virus, but it was reactivated, and as of the blood work last week, still is. Kind of confusing....

    Current Treatment:
    Daily Medications: Elmiron, Cymbalta, Baclofen, Nexium, Pyridium, Adderall, Tramadol, Kolonpin, Tetracycline
    Other: Self-Hypnosis, IC Diet, exercise, IV drips 2x a week of a bunch of stuff...


    Here is the test to find whether your mission on Earth is finished: if you're alive, it isn't. " -Richard Bach"

    [/I"]:woohoo: So, I know everyone knows this already, but I just thought I'd remind everyone about how the Saints are going to win the Superbowl this year, so, yeahh...ThE sAiNts,in tHe DoMe...'nuff said
    Tags: None
  • #2
    Wow! I thought it was an industrial solvent and since it certainly feels like one, I have kind of kept that belief. I know someone on the boards had it leak into their other organs and mess things up really bad because of the rate of absorption. My current Uro won't even consider using the stuff. Thank God. What the hell is this stuff, it is an interesting subject to ponder.
    I was born with one ureta not attached to it's kidney, I've been poked and prodded for so long. I never had "private" parts. I had constant infections and took low dose preventive antibiotics into my teens.

    DX with IC July 1993 after seeing 3 different Uro's and finally switching Primary care doctors and affiliated hospitals.

    I have 2 beautiful daughters, the oldest has been in heaven since she was 14 when she was hit by a car The youngest is 20 now. She has had one UTI. She went into complete panic that she would end up like me. Now she has some idea of what the pain is like. Poor kid has been forced to know where every bathroom in Disney World is.

    Comment

    • #3
      Dimethyl sulfoxide (DMSO) is a solvent made from wood pulp. Its therapeutic uses are based on its ability to penetrate the skin. Its use remains controversial but it is very effective at carrying substances though the skin.



      # Dimethyl Sulfoxide. A solvent and penetrant so effective that it can be tasted in the mouth shortly after it is applied to the skin. DMSO is often used as an anti-inflammatory, free-radical scavenger, or mixed with antiseptic to treat localized infection

      DiMethyl SulfOxide - An industrial solvent sometimes used topically to reduce pain and swelling, and as a drug-delivery system, because it penetrates the skin quickly and deeply without damaging it. You can get DMSO at any veterinarian or health food store. Do not use it at a greater strength than 50% since the higher strengths might be irritating to sensitive skin.

      Solvent (liquid capable of dissolving things) that easily penetrates the skin. It is a dangerous, unproven "remedy" for the pain and inflammation of arthritic disorders.

      Dimethyl sulfoxide, a solvent which is an organic chemical that readily passes through the skin. Anti-inflammatory, antibacterial and analgesic

      The Human Toxicology Of Dimethyl Sulfoxide
      http://www.dmso.org/articles/information/brobyn.html
      Dr. Stanley Jacob, the father of DMSO offers information on DMSO & MSM. DMSO (dimethyl sulfoxide), a potent scavenger of free radicals, was first introduced to the scientific community in 1963 by a research team headed by Stanley W. Jacob, MD.


      Dimethyl sulfoxide (DMSO), a by-product of the wood industry, has been in use as a commercial solvent since 1953. read on here
      DMSO: Many Uses, Much Controversy
      http://www.dmso.org/articles/information/muir.htm
      Dr. Stanley Jacob, the father of DMSO offers information on DMSO & MSM. DMSO (dimethyl sulfoxide), a potent scavenger of free radicals, was first introduced to the scientific community in 1963 by a research team headed by Stanley W. Jacob, MD.


      A wide range of primary pharmacological actions of dimethyl sulfoxide (DMSO) has been documented in laboratory studies: membrane transport, effects on connective tissue, anti-inflammation, nerve blockade (analgesia), bacteriostasis, diuresis, enhancements or reduction of the effectiveness of other drugs, cholinesterase inhibition, nonspecific enhancement of resistance to infection, vasodilation, muscle relaxation, antagonism to platelet aggregation, and influence on serum cholesterol in emperimental hypercholesterolemia. This substance induces differntiation and function of leukemic and other malignant cells. DMSO also has prophylactic radioprotective properties and cryoprotective actions. It protects against ischemic injury. read more here: http://www.dmso.org/articles/information/herschler.htm
      DMSO can actually help you, I do know that my mom had, had it done for many many years, it helped her greatly, and still today she said if they still did it she would have one done if she needed it. They did stop using it, because of the danger in long term affects. It would be good for a short term treatment, and then wait a few months to try again. I like you was confused why they would use a commercial solvent in ones bladder. My doctor dose not do them. If you type in google What is DMSO? you will a ton of information.
      'The will of God will never take you where the Grace of God will not protect you.'

      Comment

      • #4
        Cindy is always the one to provide the good info. It is an industrial solvent. I am doing DMSO right now. It comes out of the bottle at 50% solution and this seems to be what a lot of uros use. I read an article on this actual forum that says that anything stronger than 25% can cause permanant damage to the bladder muscle which I surely didn't want so I told them to do 25% which they are now.

        I haven't seen any improvement from it as of yet. I actually almost feel worse than I did before I started it but that's just me, many say it has helped them. I'm going to try to stick it out to 6 treatments because the dr really wants me to give it a chance to work but I personally don't like it so far.
        Christine



        I have been diagnoised for 6 1/2 years now. I have taken a long break from the ICN but really miss helping out my fellow IC patients and want to get back into posting.
        1st hydro 4/07 showed no visible signs of IC but tons of mast cells in all my biopsy samples which did prove IC.
        2nd hydro 4/13/09 showed dark purple glomerulations and I had a capacity of 450 cc's. This hydro proved that my IC had progressed.
        I have tried every oral medication as well as rescue instills and DMSO.

        I have been lucky enough to see Dr Hanno, the top IC specialist in PA who has told me due to the fact that I have not responded to any "standard" treatments that I have a severe, end stage case of IC with a horrible quality of life (didn't have to tell me that last part!)

        Proud wifey of Shane, mommy to Griffin, and step-mom to Logan and Gage
        Also proud mom to the best Bullmastiff on earth, Claus

        Comment

        • #5
          I unfortunately had very short term relief from DSMO that was not worth the bad side affects ( I literally REEKED like rotten garlic for a few days afterward and started flaring badly after the 2nd treatment). I tried it for 4 sessions and then was told to try something different. It may be worth a try for you. Even though it didn't work for me, I was able to move on to something else by ruling out DSMO treatments. Many Doctors will want their IC patients to try the conventional treatments (Elmiron, Elavil, DSMO, rescue treatments, etc.) first. For me, everything has really been trial and error, from foods to treatments and even the ones that didn't work or gave me side affects that I couldn't tolerate were worth a shot. If nothing else I was able to get a referall to an IC specialist after my DSMO experience.
          Let us know how you make out!
          Rachel
          DX's:
          IC; PFD; possible Fibromyalgia; IBS;

          Symptoms: Frequency, Urgency, pelvic and bladder pain, bladder and pelvic spasms, difficulty starting urination, weak stream, incontinence, vaginal and urethral pain

          I've Tried:
          three Hydrodistentions, various Rescue Installments; 6 DSMO treatments; Pyridium Plus; Proced; Detrol (patch); Elavil; Uricet K; Elmiron; Nortiptyline; Ultram; Allegra; Ditropan; Ditropan ER; Vesicare; regular Lidocain; Neurontin; Lyrica; and few more I can't remember!
          Currently using:
          Valium; Vicadin; Proced DS; Claritin; Buffered Lidocain; Cymbalta; Baclofen; Prazosin @ night (also on Prednisone and Adderall for my joint pain and severe fatigue)
          Heating pads; frozen water bottles; A&D ointment; Poise pads; IC dieter since 8/06; yoga; imagery & relaxation CD, Mindfullness, self healing CD's; hot baths; seat cushion; prayer
          I am 28 yrs old, dx'ed in '06, still trying to get my health undercontrol!!

          Comment

          • #6
            I think it took my mom 5 or 6 times to get relief, whe the office stopped using them, they srarted hydros.
            'The will of God will never take you where the Grace of God will not protect you.'

            Comment

            • #7
              Hey guys,
              Sorry its been so long, I'm playing musical computers right now. Mine had to be sent back to Apple for a repair, well actally its stills sitting in the box on the counter. I'm never gonna get it back if I dont send it! lol Anyway, im bumming both my mom and dad's comps right now cuz i had so much stuff to back up! I don't have too much time right now b/c I have an appt at 8, but I kinda skimmed it until I get a chance to thoroughly read it. What surprises me is that with all the stuff I have read on IC and, well, every other issue I have, as well as treatments (no matter how bizarre or rediculous... I'm sure you understand..lol,) I seem to have completely missed the issue w/ DMSO.
              I think on eof the reasons that it never caught my attn until now is because my uro has always acted like it was pretty much the routine thing they did in the office... you know, like no big deal... he made it seem like it was what all the cool IC patients were doing...lol Anyway, I'm gonna see what else i can dig up on it. Oh, one more thing... has anyone tried Limu?

              And i just have to tell everyone that I don't have a clue why, especially b/c I'm on my way to the doc., but I'm just in a fabulous mood today!! :woohoo: okie dokie, i hope everyone else can be as chipper as I am today, and if you can't... theres always tomorrow! ToOtLes!!

              Diagnosed: IC-2004' Endometriosis- 2000,TMJ - 2004, Osteoporosis-2005, IBS - 2005
              Peptic Ulcer-2005, PFD-2005, CFS - 2006, ADD - 1996 Bipolar disorder -2007. Other shinanigans: pelvic adhesions, Migraines, Cluster Headaches, fatigue, stomach ulcers, ovarian cysts, allergies, severe PMS.[/COLOR]
              Since February, I have had MRSA 7 times, was hospitalized for IV a/bs, and will be taking Tetracycline for the next 6 months. In April, my gyno found that not only did I also have a currently active infection of Epstein Barr Virus, but it was reactivated, and as of the blood work last week, still is. Kind of confusing....

              Current Treatment:
              Daily Medications: Elmiron, Cymbalta, Baclofen, Nexium, Pyridium, Adderall, Tramadol, Kolonpin, Tetracycline
              Other: Self-Hypnosis, IC Diet, exercise, IV drips 2x a week of a bunch of stuff...


              Here is the test to find whether your mission on Earth is finished: if you're alive, it isn't. " -Richard Bach"

              [/I"]:woohoo: So, I know everyone knows this already, but I just thought I'd remind everyone about how the Saints are going to win the Superbowl this year, so, yeahh...ThE sAiNts,in tHe DoMe...'nuff said

              Comment

              • #8
                There's information about one brand of Limu at http://www.fda.gov/bbs/topics/NEWS/2003/NEW00976.html

                Donna
                Stay safe


                Elmiron Eye Disease Information Center - https://www.ic-network.com/elmiron-p...mation-center/
                Elmiron Eye Disease Fact Sheet (Downloadable) - https://www.ic-network.com/wp-conten...nFactSheet.pdf

                Have you checked the ICN Shop?
                Click on ICN Shop at the top of this page. You'll find Bladder Builder and Bladder Rest, both of which we are finding have excellent results.

                Patient Help: http://www.ic-network.com/patientlinks.html

                Sub-types https://www.ic-network.com/five-pote...markably-well/

                Diet list: https://www.ic-network.com/interstitial-cystitis-diet/

                AUA Guidelines: https://www.ic-network.com/aua-guide...tial-cystitis/

                I am not a medical authority nor do I offer medical advice. In all cases, I strongly encourage you to discuss your medical treatment with your personal medical care provider. Only they can, and should, give medical recommendations to you.                 [3MG]

                Anyone who says something is foolproof hasn't met a determined fool

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