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  • Question about Cipro and Diflucan.

    I would greatly appreciate it if someone could let me know if they have ever taken Diflucan (Fluconazole) at the same time they were taking Cipro?

    Is it safe? I can feel that I have major yeast which is no surprise since I have taken 4 antibiotics in 4 months for a recurring UTI (though I am hoping the Cipro I am currently on will finally kill this beast since Keflex and Augmentin have not).

    Has anyone taken both drugs at the same time (meaning in the same day)?
    Medical Conditions:

    Severe IC
    IBS
    Vulvadynia
    Fibromyalgia
    GERD
    Polycystic Ovarian Disease
    Hypothyroidism
    Hashimoto's
    Epstein Barr
    Insulin Resistence
    Gout
    Breast Cancer survivor
    Monthly Vertigo (near periods)

    Current medications:

    Elavil 50mg
    Neurontin 300mg-600mgs per day
    Librax (lifesaver) as needed
    Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
    Hydroxyzine 25mg's
    Azo Cranberry 3 tablets per day
    Cipro as needed to keep UTI's at bay
    Xanax 1mg at night for sleep
    Levothyroxine 1.75 per day
    Prevacid 30mg's per day
    Zantac 150 mgs per day
    Mucinex 600mg's for Fibro
    Diflucan 150mg's after each period
    Goldenseal to keep UTI's at bay (it works)!
    Prelief as needed

  • #2
    P.S.

    This stuff makes you feel like hell (Cipro) and the "AskAPatient" reviews from patients is not exactly reassuring. Kind of scary actually. Did not realize how severe the side effects were, but I do not know what else to do. All the other antiobiotics have failed me. Not sure I can even continue taking this whole course of Cipro. Everything aches even though the urinary pain is abating somewhat. What a freaking nightmare this has been for me.
    Medical Conditions:

    Severe IC
    IBS
    Vulvadynia
    Fibromyalgia
    GERD
    Polycystic Ovarian Disease
    Hypothyroidism
    Hashimoto's
    Epstein Barr
    Insulin Resistence
    Gout
    Breast Cancer survivor
    Monthly Vertigo (near periods)

    Current medications:

    Elavil 50mg
    Neurontin 300mg-600mgs per day
    Librax (lifesaver) as needed
    Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
    Hydroxyzine 25mg's
    Azo Cranberry 3 tablets per day
    Cipro as needed to keep UTI's at bay
    Xanax 1mg at night for sleep
    Levothyroxine 1.75 per day
    Prevacid 30mg's per day
    Zantac 150 mgs per day
    Mucinex 600mg's for Fibro
    Diflucan 150mg's after each period
    Goldenseal to keep UTI's at bay (it works)!
    Prelief as needed

    Comment


    • #3
      I personally have taken the two meds together without any issues. If you're concerned based on your own medical history don't hesitate to phone your rxing pharmacist.
      (\__/)
      (o.O )
      (> < ) This is Bunny. He's on his way to world domination.

      Comment


      • #4
        Thank you so much for taking the time to answer. It means a lot when you are going through what all of us are enduring. I am not so sure I am going to be able to continue the Cipro so I may just try to get one last dose in and then take the Diflucan. The Cipro makes me feel like I have the flu. I want to scream right now. The infection did not respond to Augmentin or Keflex. Macrobid makes me ill and I am allergic to Sulfa meds which are the best and now the Cipro is making me really ill. You really feel it. I liked the Augmentin because I hardly noticed it was there, but it did nothing for me and yet the Cipro makes it real clear it's in my bloodstream.

        I wonder if others felt sick on Cipro out here even though it helped their infection? In any event thanks again for your help.
        Medical Conditions:

        Severe IC
        IBS
        Vulvadynia
        Fibromyalgia
        GERD
        Polycystic Ovarian Disease
        Hypothyroidism
        Hashimoto's
        Epstein Barr
        Insulin Resistence
        Gout
        Breast Cancer survivor
        Monthly Vertigo (near periods)

        Current medications:

        Elavil 50mg
        Neurontin 300mg-600mgs per day
        Librax (lifesaver) as needed
        Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
        Hydroxyzine 25mg's
        Azo Cranberry 3 tablets per day
        Cipro as needed to keep UTI's at bay
        Xanax 1mg at night for sleep
        Levothyroxine 1.75 per day
        Prevacid 30mg's per day
        Zantac 150 mgs per day
        Mucinex 600mg's for Fibro
        Diflucan 150mg's after each period
        Goldenseal to keep UTI's at bay (it works)!
        Prelief as needed

        Comment


        • #5
          Taking Cipro and Diflulcan

          Hi
          I have just come off a course of Cipro. I felt about the same as you do while taking it. I felt awful with the bladder infection, which apparently was a major one. I felt really awful while the Cipro. was in my blood stream but the day after I stopped it I felt quite a bit better.
          My understanding from friends and my pharmacist is that the Cipro. is the antibiotic that will go full force and attack the bacteria in our system. I think it did for me. I can really tell that the infection (at least) is not in my body.

          Holy smoke I wish I could say the same about the I.C.!

          Comment


          • #6
            God I can't believe how flu like I feel. Joint and neck pain everywhere (shoulder has been aching). I had to stop however the good news is that my Azo strip is finally clear! It has been that awful Eggplant purple color through all the courses of Augmentin and Keflex and would never go away (or the horrible symtoms). I finally got a clear test result for the first time ever after taking three 500 mg doses of Cipro for two days. I just can't take another one. I feel sick already from it. It has been the only antibiotic to touch this infection however I feel really ill from it in general (traded one pain for many others).

            I did some research and apparently studies have been done showing that one single 500 mg Cipro is usually enough for a UTI even though much more is prescribed. I believe it after seeing what it did in just three doses! This might be the perfect answer to that antibiotic I was searching for that I could take one of of after each period to stop getting infections however, I am not so sure I can deal with these serious side effects (many have reported permanent nuerological damage as well as the Achilles Heel tearing)! I was stunned as I realize that all drugs have side effects, but I bet you have never seen one with this many serious side effects reported earning them a new black box the label (I went to Drugs.com and was mortified). These are not garden variety risks.

            I was OK after the one dose, but it was a completely different story after the second so if one is enough, it might be the answer. Also I found that some are prescribed only 250mg to be taken once a day for three days and I had 500 mg to be taken twice a day and so I do feel that is overkill. I just pray it stays away because none of the other antibiotics would touch it!

            Thanks for yuour input. It is greatly appreciated more than you know.
            Medical Conditions:

            Severe IC
            IBS
            Vulvadynia
            Fibromyalgia
            GERD
            Polycystic Ovarian Disease
            Hypothyroidism
            Hashimoto's
            Epstein Barr
            Insulin Resistence
            Gout
            Breast Cancer survivor
            Monthly Vertigo (near periods)

            Current medications:

            Elavil 50mg
            Neurontin 300mg-600mgs per day
            Librax (lifesaver) as needed
            Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
            Hydroxyzine 25mg's
            Azo Cranberry 3 tablets per day
            Cipro as needed to keep UTI's at bay
            Xanax 1mg at night for sleep
            Levothyroxine 1.75 per day
            Prevacid 30mg's per day
            Zantac 150 mgs per day
            Mucinex 600mg's for Fibro
            Diflucan 150mg's after each period
            Goldenseal to keep UTI's at bay (it works)!
            Prelief as needed

            Comment


            • #7
              Like mentioned all meds come with side effects. If one ever took the time to read about the possible side effects from a simple aspirin nobody would take another one.
              I always request Cipro as I know its the drug that kills the majority of bacteria with less doses. I'm fortunate enough to have never experienced any symptoms like you've mentioned. I have though had terrible gastric symptoms from other abx, mainly amoxicillin.
              Have you thought about asking your Dr for a prophylactic abx? This treatment is rx'd as daily doses, every other day doses, once per week, or only after intercourse. If you're prone to UTI's (more than 3 per year) it might not be a bad idea to run this by your Dr and see what his/her opinion might be.

              Hope you continue to improve.
              D
              (\__/)
              (o.O )
              (> < ) This is Bunny. He's on his way to world domination.

              Comment


              • #8
                Thank you for your suggestion. I do plan on asking about this when I go in for a follow up (that's what I meant when I said I had been looking into antibiotics that can be taken in one or two doses after each period).

                I do have to say that Cipro is in a class of it's own as far as serious side effects. I say this because I really did research this and this can be a very dangerous drug actually (more than most that's for darn sure). I know that they all have their potential but there were hundreds upon hundreds of people at Ask A Patient that said this drug destroyed their lives and they are in constant pain. They seemed rather sincere and since I am feeling some of what they are warning about, I have to concur. Obviously drugs like anything else work differently for different people however I am not feeling very well after taking this and hoping it will fade away and be temporary.

                It has cleared this infection and for that I am truly grateful but the intense headache, shoulder pain, joint and muscle issues are extreme and came on right after I began to take this. I honestly feel like I have the flue which is what many of these patients were describing to a tee. Hopefully they will be gone soon.
                Medical Conditions:

                Severe IC
                IBS
                Vulvadynia
                Fibromyalgia
                GERD
                Polycystic Ovarian Disease
                Hypothyroidism
                Hashimoto's
                Epstein Barr
                Insulin Resistence
                Gout
                Breast Cancer survivor
                Monthly Vertigo (near periods)

                Current medications:

                Elavil 50mg
                Neurontin 300mg-600mgs per day
                Librax (lifesaver) as needed
                Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
                Hydroxyzine 25mg's
                Azo Cranberry 3 tablets per day
                Cipro as needed to keep UTI's at bay
                Xanax 1mg at night for sleep
                Levothyroxine 1.75 per day
                Prevacid 30mg's per day
                Zantac 150 mgs per day
                Mucinex 600mg's for Fibro
                Diflucan 150mg's after each period
                Goldenseal to keep UTI's at bay (it works)!
                Prelief as needed

                Comment


                • #9
                  If your symptoms continue after you stop the medicine.. It might be a good idea to have some test run.. Because the flu is going around!!

                  Hugs
                  Hugs
                  Ronda

                  ONE Second, ONE Bite, ONE Breath, ONE Pill, ONE Minute, ONE Teardrop, ONE Hour, ONE Sip.. ONE DAY! I will Prevail from this disease! IC Hoping for a Cure!


                  Link to Patient Handbook:
                  http://www.ic-network.com/handbook/

                  Diet Reference Sheet:
                  http://www.ic-network.com/diet/icndi...tsheet0909.pdf

                  Meds For IC: Lyrica-25mg Glucosamine-500 MSM-500mg, Prosed Ds -When Flaring

                  Other Meds: Levlite- Continious Birtcontrol, Micardis-40mg for High Blood Pressure

                  Meds I have Tried:
                  Topamax,Tofranil, Elmiron, Atarax, Cymbalta, Elavil, Enablex, Detral La, Prydium.
                  Lexapro< Bad reaction to this med!
                  Intstills, could not continue them due to some kind of reaction after 3rd instill. Tasted the lidocaine in my mouth, tongue and lips went numb then went into what seemed like a panic attack. Shaking, racing heart, tingling face/head, blood pressure shot up..

                  Dx With IC in Nov 2006 with Hydro/Cysto
                  Hydro/Cysto Caused Bladder to Rupture.

                  Other Dxs-Vulvodynia,Fibro, Endo, IBS, HPV, Migraines, Spastic Colon, Mild Dysplasia.



                  ICN Volunteers are not medical authorities nor do we offer medical advice. In all cases, we strongly encourage you to discuss your medical treatment with your personal medical care provider. Only they can, and should, give medical recommendations to you.

                  Comment


                  • #10
                    I was just thinking that too. I am going to ask if they can run blood work when I go in next week for my follow up. That would be all I need right now is the flu (I have a colonoscopy scheduled for mid October so I need to find some peace before then you know)! I am one of those people that takes forever to heal. Ever since my breast cancer my system has been a mess. God I hope it's just the drug abnd not the flu.

                    P.S. I have been a little worried about serum sickness because I have been on 4 courses of antibiotics now in 4 months.
                    Medical Conditions:

                    Severe IC
                    IBS
                    Vulvadynia
                    Fibromyalgia
                    GERD
                    Polycystic Ovarian Disease
                    Hypothyroidism
                    Hashimoto's
                    Epstein Barr
                    Insulin Resistence
                    Gout
                    Breast Cancer survivor
                    Monthly Vertigo (near periods)

                    Current medications:

                    Elavil 50mg
                    Neurontin 300mg-600mgs per day
                    Librax (lifesaver) as needed
                    Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
                    Hydroxyzine 25mg's
                    Azo Cranberry 3 tablets per day
                    Cipro as needed to keep UTI's at bay
                    Xanax 1mg at night for sleep
                    Levothyroxine 1.75 per day
                    Prevacid 30mg's per day
                    Zantac 150 mgs per day
                    Mucinex 600mg's for Fibro
                    Diflucan 150mg's after each period
                    Goldenseal to keep UTI's at bay (it works)!
                    Prelief as needed

                    Comment


                    • #11
                      It turns out that all that flu like stuff was the Cipro and not the flu. I will say this though. Cipro is the bomb because it killed what the others could not even touch. I am also basically OK if I just take one dose and in studies done on this drug, one dose of Cipro out performed a full course of several others antibiotics tested against it. Because I am so prone to infection which in turn causes me severe pain, I am going to start taking 1 (250) mg dose each month after my period ends and go from there. I only took three pills and yet the infection is gone still (test strip clear). I like that you do not truly need to overdo it and take more of this particular one. The side effects are pretty horrendous but if I can get buy with one or two doses, I can hang.

                      The Cipro wiped out so much pain!
                      Medical Conditions:

                      Severe IC
                      IBS
                      Vulvadynia
                      Fibromyalgia
                      GERD
                      Polycystic Ovarian Disease
                      Hypothyroidism
                      Hashimoto's
                      Epstein Barr
                      Insulin Resistence
                      Gout
                      Breast Cancer survivor
                      Monthly Vertigo (near periods)

                      Current medications:

                      Elavil 50mg
                      Neurontin 300mg-600mgs per day
                      Librax (lifesaver) as needed
                      Percocet (1) 325mg for rescue flares only (usually 2-3 per month)
                      Hydroxyzine 25mg's
                      Azo Cranberry 3 tablets per day
                      Cipro as needed to keep UTI's at bay
                      Xanax 1mg at night for sleep
                      Levothyroxine 1.75 per day
                      Prevacid 30mg's per day
                      Zantac 150 mgs per day
                      Mucinex 600mg's for Fibro
                      Diflucan 150mg's after each period
                      Goldenseal to keep UTI's at bay (it works)!
                      Prelief as needed

                      Comment


                      • #12
                        Just wanted to say that I have been on Cipro several times for bladder infections (last time for a 8 days) and I didn't have any side effects at all for me that I noticed so far anyway and I finished a couple of months ago. I didn't know enough to be worried and my uro prescribed them without a word of caution. Thanks for the heads up if I need them again!

                        And I did go from bacteria to a clear urine culture with them. I have been taking vaginal flora probiotics since as I am sure it imbalanced every thing down there...
                        -Not officially diagnosed with IC but have had several inconclusive work-ups for it after several months-long bouts of frequency, soreness, and the insomnia that goes with it.

                        -long stretches of being symptom-free in between

                        -currently on low dose bcps, celexa, and Estrace cream for possible hormonal role in bladder symptoms (I'm 45)

                        Comment


                        • #13
                          Using antibiotics

                          I've found antibiotics usually make me feel better, even though it doesn't cure any thing for IC. Urologists seem to like Levaquin and Macrobid for UTIs. I'm allergic to Levaquin and don't like how I feel on Macrobid - two different things. I noticed minor relief from using L. Casei probiotics (in Dan Active). Acidophilus probiotic pills will help with preventing yeast infections, but it needs to be used every other day prior to an infection or use of antibiotics. My pharamacist told me to eat a standard yogurt with acidophilis 2 hrs b4 using an antibiotic and 2 hrs after - to help with yeast prevention and to replace good bacteria that the antibiotic kills off.

                          What's difficult for me about IC is knowing if I have a real bladder infection or not. Most often when my urine was cultured, there was no infection. For 2 yrs I've been confused if pain and spasming signals a UTI or not. I was told it was my pelvic floor (tight) muscles that probably caused the bladder to be disturbed, causing pain and spasming. I do have some scar tissue from a hysterectomy right over my bladder (that can tear with activity that makes use of the muscles in that area.) Bladder 'inflammation' will always cause some type of discomfort and I've finally accepted that.

                          For a unrelated skin infection I was given Doxycycline, which greatly improved my IC. I was on it for 4 weeks. It went to war on something in my pelvic area that other antibiotics didn't notice? I also use Dan Active daily (yogurt drink), as it seems to calm my bladder. I use acidophilus 2-3x wk, but it makes me hungry 1 hr after eating. Now I'm trying L. Reuteri (probiotic pill) as clinical studies suggest it may be helpful to pelvic/bladder area. Not all probiotics are equal. I avoid Activia (Bifidus, Bifido bacterium, BB-12, etc.) as it causes frequency in me. If you use a probiotic, pay attention to how you feel within 90 minutes. And, many antibiotics make me feel ill, especially in the area it's attacking - that's OK initially unless it's the bad reactions like hives, breathing...things on the warning labels. I now keep tract of how I feel when trying something new.

                          11-2010 update: The Doxycycline in 2009 gave me long-term relief from most of my IC pain - implying I had a pelvic infection that was unresolved by other antibiotics and undetected by all types of testing. I also no longer have blood in my urine, and don't have the symptoms of bladder UTIs. I had to repeat the Doxycline treatment about 6 months later. Waiting to see if it comes back in another six months. But, life is less scary now. I continue to use Detrol for frequency and probiotics for day-to-day health.
                          Last edited by karenann52; 11-20-2010, 03:41 AM. Reason: insight with hindsight

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