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tell me why again?

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  • tell me why again?

    Why I am taking an antidepressant and an antihistamein with the elmiron?

  • #2
    Elmiron can take up to six months or longer to become effective --- and even then it is not always complete relief. Sometimes it can take combinations of medications to give us relief. Is the combination helping you to feel better?

    Warm healing thoughts,
    Stay safe

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    I am not a medical authority nor do I offer medical advice. In all cases, I strongly encourage you to discuss your medical treatment with your personal medical care provider. Only they can, and should, give medical recommendations to you.

    Anyone who says something is foolproof hasn't met a determined fool


    • #3
      <icnmgrjill> You've also championed the use of hydroxyzine with or without Elmiron. Can you tell us more about your recent observations??

      <drparsons> For years now, I've had both drugs and used them extensively in several thousand patients. I would simply summarize by saying that Elmiron is the cornerstone to rebuild the bladder surface but allergies are frequently what is breaking it down and you need hydroxyzine for that. Give me hydroxyzine and Elmiron and I can make 90% of my patients better and keep them better. At least 70% of patients need both medications and they will always need both.

      Most of my patients tend to stop the Atarax but they will pay a price if they flare during the allergy. They will take three months to really improve again. One bad allergy flare and they usually listen to me. You only need a low dose hydroxyzine.. 25 mgs at bedtime. I think that it is far more important than Elavil.

      Tricyclic Antidepressants: ELAVIL & TOFRANIL
      Elavil® (amitryptyline) is a tricyclic antidepressant that, in low doses, is effective at relieving chronic pain by interfering with nerve activity. It is commonly prescribed for several chronic pain conditions, including irritable bowel syndrome (IBS) and fibromyalgia, two conditions that many IC patients also have. Its strength as a long-term pain management strategy, an essential part of an IC tool kit, makes it helpful in treating IC. It also may inhibit bladder spasms.
      Several studies have reported a positive response with amitriptyline (9,10). Hanno (11) reports that amitriptyline was quite effective for patients who had not responded to hydrodistention and DMSO. Amitriptyline has side effects which merit consideration prior to taking it, including dry mouth, drowsiness and, for some patients, cardiac arrhythmias (irregular heart rate) and tachycardia (rapid heart rate).

      Other antidepressants, such as Tofranil® (imiprimine), Prozac® and a host of others, may be options for physicians to consider. Amitriptyline, however, remains the most extensively tested medication of this type for IC.

      Diagnosed August 2001

      Current IC meds: Elmiron (since 2001), Levaquin (one pill after intercourse to prevent UTIs), Effexor (for depression & anxiety)

      Past IC meds: Amitriptyline (Elavil), Hydroxyzine (Vistaril), Detrol LA, Lexapro (for depression & anxiety, but also helped my IC) (They all helped, but I was able to discontinue them.)

      I've been virtually symptom free and able to eat & drink whatever I'd like for about 8 years now.


      “We who lived in concentration camps can remember the men who walked through the huts comforting others, giving away their last piece of bread. They may have been few in number, but they offer sufficient proof that everything can be taken from a man but one thing: the last of the human freedoms -- to choose one's attitude in any given set of circumstances, to choose one's own way.” ~ Viktor Frankl

      “You cannot control what happens to you, but you can control your attitude toward what happens to you, and in that, you will be mastering change rather than allowing it to master you.” ~ Brian Tracy