I have been on Amitriptyline for almost 2 years now. It has helped my IC tremendously but I have also gained about 20 lbs. At first I thought the weight gain was due to thyroid problems but my thyroid levels have been normal for a while now and I am still gaining weight.

I have tried to wein (sp?) myself off of amitriptyline before but everytime my IC has gotten worse.

I don't want to be in pain but I don't want to keep gaining weight either. Has anyone tried another med in place of amitriptyline and had success with it or have any suggestions of what I could do about this? Thanks!