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  • #1

    Hydroxyzine Question

    Can hydroxyzine cause more frequency?

    I started med 3 days ago 3x a day 25 mg. Maybe I am in a flare but it seems worse since I started this med. I have to go every 40 minutes now and feel like I have to go again after I go.

    How long does it take for hydroxyzine to work/help with frequency?

    I've also been taking elmiron 300 mg a day for 3 months now. I have tried sanctura several times but stopped it because of retention, but seems retention is better than feeling like I have to go all the time. Maybe there is a better OAB med out there for me.

    Can you take an OAB med successfully with hydroxyzine?

    I am just getting impatient waiting on these meds to help. I am getting so confused

    Any advice would be appreciated THANKS!!

    God Bless,
    Jonathan
    Tags: None
  • #2
    Hi, yes this happened to me. I heard its happened to others also. Then they said that after a couple of weeks they felt better. some people are also sensitive to some of the fillers in the medicine. I suggest you consult your doctor and see if he/she would like you to stay on. this medicine can take 3 months to kick in. for some it takes much longer to calm down the mast cells on the bladder causing pain .though most people see results sooner. OAB meds cause me retention. You might can ask your doctor for a lower dosage. good luck
    Diagnosed with IC October 2009- through bladder biopsy (no glomerations or hunners ulcers found, just irritation)

    I have moderate-severe IC

    Currently stopped taking all medications due to pregnancy

    Comment

    • #3
      I feel like hydroxyzine increases my frequency also. Benadryl too.
      ~Ashley

      Comment

      • #4
        Originally posted by jonb1 View Post
        Can hydroxyzine cause more frequency?

        I started med 3 days ago 3x a day 25 mg. Maybe I am in a flare but it seems worse since I started this med. I have to go every 40 minutes now and feel like I have to go again after I go.

        How long does it take for hydroxyzine to work/help with frequency?

        I've also been taking elmiron 300 mg a day for 3 months now. I have tried sanctura several times but stopped it because of retention, but seems retention is better than feeling like I have to go all the time. Maybe there is a better OAB med out there for me.

        Can you take an OAB med successfully with hydroxyzine?

        I am just getting impatient waiting on these meds to help. I am getting so confused

        Any advice would be appreciated THANKS!!

        God Bless,
        Jonathan
        It flared me badly but it works wonders for some people. It's always rough when a med does not work out. I try very hard not to get my hopes up and to be patient. It's rough though.

        Love, H.

        Comment

        • #5
          Vesicare

          Hi Jonathon,

          I have taken hydroxizine but not on a regular basis because it seriously makes me so tired the next day and I work very long hours with no caffeine...so I really havent been able to stick with it. As far as helping me with frequency, I started Vesicare a few weeks ago and I've really noticed a reduction in my frequency. It made a world of difference even the first few days. I was going every hour and 15 and can now make it to every 3 hours. I take 5 mg. Hope that helps!

          Comment

          • #6
            Originally posted by WhitneyWonders View Post
            Hi Jonathon,

            I have taken hydroxizine but not on a regular basis because it seriously makes me so tired the next day and I work very long hours with no caffeine...so I really havent been able to stick with it. As far as helping me with frequency, I started Vesicare a few weeks ago and I've really noticed a reduction in my frequency. It made a world of difference even the first few days. I was going every hour and 15 and can now make it to every 3 hours. I take 5 mg. Hope that helps!
            Thanks Whitney, Right now I am just taking Elmiron, I still may try vesicare or even ditropan. Sanctura and enablex didn't work. Most days are better than others, but I am still trying to get the frequency down. THANKS and I hope you are doing great!!!!!!!
            Jonathan

            Comment

            • #7
              Hi Jonathan, just wanted to say I take vesicare and like Whitney it greatly reduces my frequency, especially that feeling that you gotta go when you really don't, I think that is called urge. I take 5mg also. I have used ditropan xl also, for a couple years but for me anyway, it didn't work as well. Without the vesicare I feel like I gotta go an hour after I last went, sometimes sooner. With the vesicare I can go anywhere from 2-3 1/2 hours or so. It is drying so I was going to try taking it every 36 hours or every 48 to see where exactly it wears off. Makes it hard to wear my contacts but worth it some days!

              One thing I've noticed while I take it is you don't want to go to the bathroom before your body says "gotta go" or you'll feel like its hard to go. I think we all get used to going so frequently that after a certain time period goes by we try and go by default

              I think its fine to take with hydroxyzine but you can double check with your pharmacy. One is a anticholinergenic and one is a antihystamine.
              Cindi


              Gelnique for frequency/urgency - works great
              Macrobid after sex
              Prilosec, continuous birth control pills
              synthroid .088mg, mucinex-d, restasis

              Supplements: Desert Harvest Aloe vera, Cysta-q, prelief, magnesium and calcium, Vit D, flaxseed oil

              Diag Mild IC Jan 11 but have had symptoms for 25 years. Also have GERD, TMJ, IBS-C, chronic dry eye syndrome, hashimotos thyroiditis, non-allergic rhinitis.

              IC Diet Link: http://www.ic-network.com/diet/2009icdietlist.pdf
              AUA 2011 Guidelines to diagnosing and treating IC overview- http://www.ic-network.com/forum/showthread.php?p=571592
              AUA 2011 Guidelines to diagnosing and treating IC PDF: http://www.auanet.org/content/guidel...ent_ic-bps.pdf
              Great treatment flowchart on page 19 of the pdf

              Comment

              • #8
                Be careful with the overactive bladder meds. A lot of people (including me) can't take them because they can cause retention and make you really have to push to go which just makes things a lot worse. For me those meds increase frequency. It's always worth a try, but if you experience this let your doctor know.
                ~Ashley

                Comment

                • #9
                  I agree with you Ashley, you have to be careful. It may seem like heaven to have a little break, but that could lead to bigger problems. You have to really, really be cautious and always check your ankles, etc., for any edema. The moment you have that, you need to call your doc and probably stop the vesicare. Maybe some can handle it, it just seems contradictory to me. We need to get the poisons out, not retain them. Just please be careful and monitor yourself.

                  Comment

                  • #10
                    Jill <Maybe some can handle it, it just seems contradictory to me. We need to get the poisons out, not retain them.>

                    Thats just the thing, you don't know if you don't try. If they don't cause retention then they are wonderful drugs as they relax the bladder muscle. Elavil and the tri-cyclics are also anticholinergenics and do the same thing but perhaps less at the smaller dose that
                    is usually taken.

                    I am not saying they are not for everyone but for those that don't retain or swell or anything they don't keep anything in, in fact they make it so I feel like I go more, maybe because I go longer in between. When I go it feels more "normal" if that makes any sense. I don't get that start stop sensation.

                    I realize we are all different but wanted to throw that out to him to try. How will anyone know if a med will work until they try it?
                    Cindi


                    Gelnique for frequency/urgency - works great
                    Macrobid after sex
                    Prilosec, continuous birth control pills
                    synthroid .088mg, mucinex-d, restasis

                    Supplements: Desert Harvest Aloe vera, Cysta-q, prelief, magnesium and calcium, Vit D, flaxseed oil

                    Diag Mild IC Jan 11 but have had symptoms for 25 years. Also have GERD, TMJ, IBS-C, chronic dry eye syndrome, hashimotos thyroiditis, non-allergic rhinitis.

                    IC Diet Link: http://www.ic-network.com/diet/2009icdietlist.pdf
                    AUA 2011 Guidelines to diagnosing and treating IC overview- http://www.ic-network.com/forum/showthread.php?p=571592
                    AUA 2011 Guidelines to diagnosing and treating IC PDF: http://www.auanet.org/content/guidel...ent_ic-bps.pdf
                    Great treatment flowchart on page 19 of the pdf

                    Comment

                    • #11
                      You're right, it's worth a try. I just like to warn people about it because no one warned me and I couldn't understand why my frequency was getting worse and worse while I was on an OAB med. It's great that it works for some people...it seems like a logical fix to me, but of course I have to be "different"

                      Oh BTW, I didn't have any edema or anything, but that having to push to go problem was the worst!
                      ~Ashley

                      Comment

                      • #12
                        Hello,

                        I am trying Hydroxyzine at 10mg at night before bed again, for the 2nd time and am noticing the same thing again, it's causing frequency, and I feel like I'm in a flare, but I know it's the meds and nothing else....

                        I have a perscription for Vistaril which is the Brand name Hydroxyzine, that I will be trying next, it has different fillers, so am hoping it will agree with me. *fingers crossed*

                        So frustrating.....
                        Live Well
                        Love Much
                        Laugh Often!



                        Diagnosed:
                        Dec 2005
                        Diagnosis:
                        IC
                        Cysto/Hydro:
                        Dec 2005
                        Other Conditions:
                        Anxiety, Insomnia, Chronic Sinusitis, Bursitis of the hip, Chronic Fatigue Syndrome, PFD, Inflamitory Arthritis of the neck, Allergy to Yeast and Dairy
                        Meds for IC:
                        Prosed/DS as needed which works much better for me than Pyridium, Prelief, Coffee Tamer, Claritin 5mgs and sodium bicarb as needed.
                        Alternative Treatments
                        Physical therapy for 8 weeks, Acupuncture (just started).
                        Other Meds:
                        Skelaxin (as needed)
                        Didn't work:
                        Detrol LA (didn't help symptoms), Pyridium 200mg isn't working very well anymore.
                        Tried:
                        Elmiron (Major Dizziness), Hydrodistention (Greatly exacerbated IC symptoms), Urised (hard time breathing), Ditropan (bladder pain the next day), Rescue Instillations - Lidocane, sodium bicarb (all over body rash with itching),

                        Comment

                        • #13
                          Hi Shamay,

                          I experienced the same thing with Hydroxyzine and I feel like the fillers were increasing my frequency, but at the same time it felt like it took the inflamed feeling away from my bladder. When you switched to Vistaril did you notice a difference?

                          Comment

                          • #14
                            I couldn't take hydroxizine for yrs. Then my i.c. calmed down and I was able to take it. I literally can't take any anticholinerics, even when I am in remission.
                            Dr. Theorides says that hydroxizine increases opiod action, so if I take a Percocet I take it with hydroxizine. I can't tell but I find I am taking fewer Percocets.

                            Comment

                            • #15
                              Why does hydroxizine do this with opiates? Is it the anti-depressant factor in it?
                              Teresa

                              We are not HUMAN BEINGS going through a temporary SPIRITUAL EXPERIENCE. We are SPIRITUAL BEINGS going through a temporary HUMAN EXPERIENCE....so that we may become more SPIRITUAL.

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