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Sanctura XR and cephalexin

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  • Sanctura XR and cephalexin

    I've been taking cephalexin for about 7 days now, and just started Sanctura XR a week ago. I had been on vesicare but didn't see much improvement in frequency, which is my big problem.

    I always have the worst frequency in the morning, bur my bladder usually calms down by the time i get to work. A few times in the past week i've had really bad flares causing frequency until about 1:00 in the afternoon. Then things calm down, and I urinate about every 2 hours for the rest of the day. I've also just finished my period, which also causes me flares.

    I guess I'm trying to figure out if the antibiotic, the Sanctura or my period has caused the increase frequency. I don't want to give up on the Sanctura since when i'm not flaring I'm only going everty two hours, which is longer than I lasted on vesicare.

    Any thoughts? The increased frequency is a nightmare...

  • #2
    It shouldn't be the sanctura --- it's supposed to relax those muscles. It could very well be the hormone fluctuations with your period.

    I hope you feel better soon.

    Stay safe

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    • #3
      I am on Sanctura XR 60 mg, and it really helps to control bladder spasms and pain. It has helped me through some bad retention issues, and also with the frequency. I doubt it is that medication, it has never caused me any issues, just helped. I sometimes have increased frequency with my period, when it is about to start. I will go into a flare. I am not sure about anti-biotics giving any kinds of flare-ups. I had taken one a little while ago, and it did not bother me. I really would not give up on the Sanctura XR. It really is a good medication.

      I would wait until after your period has gone, and when you are done with the keflex in order to see if that is the problem. You already have quite a few things going on, so you cannot really determine if it is the Sanctura. If you are on anti-biotics, you may be sick, or something is going on. I know when I am sick with something, my bladder will flare like crazy.

      Hope this helps. Like I said, don't give up on the Sanctura. It really is a good med.

      24 year old Ph.D student in Organic Chemistry

      Loves to listen to music, play with my animals (cat, fish, 2 hamsters), and live life to the fullest each and every day.

      My blog (just started):

      Elavil 25mg (helped with nighttime urination-used to be 7 or more times a night, now just once)
      Cymbalta 60mg
      Gabapentin (Neurontin) (3200mg/day)
      Zyrtec 10mg
      Xanax 0.5mg up to 3 times a day(spasms, anxiety)
      Macrobid 100mg (only on days when doing an instill)
      Yaz Birth Control (3 months on birth control, then period)
      Pelvic floor therapy
      Valium 5 mg (inserted vaginally)
      MScontin 30 mg (3 times a day)
      Percocet 10/325mg (every 6 hours)
      TENS Therapy, CVS machine, 30 minutes once or twice a day
      Sanctura XR 60 mg (to help control severe bladder spasms that are causing urinary retention episodes and enable normal bladder sensations)

      *** 1/4 of a teaspoon of baking soda in an 8 ounce glass of water up to 4 times a day*****


      Currently doing hyaluronic acid instillations (cystistat-6 instillations, once a week, already had 4...not sure if helping)

      Used to do these:

      Solu-Cortef (act-o-vial) 100 mg: 2 mL
      Marcaine (bupivicaine) 0.5 % 25 mL
      20,000 units Heparin
      3 mL sodium bicarbonate

      Diagnoses: Moderate IC, scoliosis, asthma, ovarian cysts, PFD, IBS, Fibromyalgia, vulvodynia, Fowler's syndrome (mild) 'Central Sensitivity Syndrome.'